Subfertile couple with t(4;22)(q23;q11.2).

نویسندگان

  • Małgorzata Srebniak
  • Lucyna Popowska
  • Angelika Wawrzkiewicz-Witkowska
  • Agnieszka Tomaszewska
  • Wojciech Kazmierczak
چکیده

A couple was referred for cytogenetic examination due to idiopathic miscarriages. The proband proved to be a carrier of chromosomal translocation and her partner's karyotype was found to be normal. The karyotype of the proband is 46,XX,t(4;22)(q23;q11.2) and can be regarded as a reason of fertility problems in the investigated couple. The risk of further miscarriages is high, but the risk of a progeny with abnormal karyotype is rather low, as the progeny would probably have lethal imbalances.

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عنوان ژورنال:
  • Journal of applied genetics

دوره 46 3  شماره 

صفحات  -

تاریخ انتشار 2005